The answer will differ depending on what is meant by 'withdrawn' presentations. Presentations that have been removed from the Marketing Authorization via variation and are no longer valid should not be visible in IRIS. If they are, please raise a ticket with EMA HelpDesk to correct it. Presentations that are no longer in the market but are still valid in the MA will be visible in IRIS. In that case, if the presentation was marketed and removed from the market later on, the status should be reported as Not Marketed. This should be done in 2 steps, first the presentation should be reported as Marketed with the date of initial placing in the market for each MS as Date of marketing status change. Once this is completed, the presentation should be reported as Not marketed and the Date of marketing status change, Reason for cessation and Does cessation leads to shortages should be populated. The 2 step approach is to allow for the date of initial placing in the market to be visible in the report. If the presentation was never on the market in a particular MS, it should be reported as Never marketed for that particular country.