Organisation address: which location to choose for a submission?

When creating a new submission and selecting the location of the company, should the address selected be the one where the company is registered ? If the company is registered in one location and has offices in another location, should this location be selected instead ?
How can I update the address of the location of the offices?
 

As mentioned in the IRIS guide for applicants, it is strongly recommended to use only one location of the parent organization for all IRIS submissions, RPIs and regulatory entitlements. The location should be the address of the legal seat of the organisation. This simplifies your management of submissions in IRIS, because after selecting a location for a draft submission, only the RPIs and Regulatory Entitlements associated to that location will be available for selection.